Andhra Pradesh BIEAP AP Inter 1st Year Zoology Study Material 9th Lesson Chemical Coordination and Integration Class 11 Textbook Exercise Questions and Answers.
Chemical Coordination and Integration Class 11 Questions and Answers AP Inter 1st Year Zoology 9th Lesson
I. Chemical Coordination and Integration Multiple Choice Questions (1 Mark)
Question 1.
Which of the following is not an endocrine gland ?
(1) Pituitary
(2) Pineal
(3) Pancreas
(4) Salivary glands
Answer:
(4) Salivary glands
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Question 2.
The posterior pituitary is under the direct neural regulation of the……….
(1) hypothalamus
(2) cerebellum
(3) epithalamus
(4) medulla oblongata
Answer:
(1) hypothalamus
Question 3.
The pituitary gland is located in a bony cavity called………..
(1) glenoid cavity
(2) acetabulum
(3) sella tursica
(4) pars intermedia
Answer:
(3) sella tursica
Question 4.
Oxytocin and vasopressin are synthesized in………
(1) posterior pituitary
(2) anterior pituitary
(3) hypothalamus
(4) thyroid
Answer:
(3) hypothalamus
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Question 5.
Excess secretion of growth hormone in adults leads to…….
(1) Dwarfism
(2) Acromegaly
(3) Graves’ disease
(4) Addison’s disease
Answer:
(2) Acromegaly
Question 6.
Which hormone stimulates contractions of the uterus at the time of child birth and milk ejection from the mammary glands?
(1) Vasopressin
(2) Oxytocin
(3) Thyroxine
(4) Insulin
Answer:
(2) Oxytocin
Question 7.
Assertion (A): Vasopressin is called antidiuretic hormone.
Reason (R) : It reduces loss of water through urine.
(1) Both (A) and (R) are true, and R is the correct explanation of (A)
(2) Both (A) and (R) are true, but R is not the correct explanation of (A)
(3) (A) is true, but (R) is false
(4) (A) is false, but (R) is true
Answer:
(1) Both (A) and (R) are true, and R is the correct explanation of (A)
Question 8.
Match the following.
| Column-I | Column-II |
| a) T4 | i) Hypothalamus |
| b) PTH | ii) Thyroid |
| c) GnRH | iii) Pituitary |
| d) LH | iv) Parathyroid |
(1) (a)-ii, (b)-iv, (c)-i, (d)-iii
(2) (a) – i, (b)- iii, (c)-iv, (d)-ii
(3) (a)-iii, (b)-ii, (c)-iv, (d)-i
(4) (a)-iv, (b)-iii, (c)-i, (d)-ii
Answer:
(1) (a)-ii, (b)-iv, (c)-i, (d)-iii
Question 9.
Circulating levels of calcium ions regulate the secretion of………
(1) parathyroid hormone
(2) adrenaline
(3) insulin
(4) glucagon
Answer:
(1) parathyroid hormone
Question 10.
Prolonged hyperglycemia leads to………
(1) Diabetes insipidus
(2) Diabetes mellitus
(3) Addison’s disease
(4) Cretinism
Answer:
(2) Diabetes mellitus
Question 11.
Which of the following is not a symptom of Cretinism ?
(1) Stunted growth
(2) Low IQ
(3) Deafness and mutism
(4) Decalcification of bones
Answer:
(4) Decalcification of bones
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Question 12.
Which of the following is mismatched ?
(1) Hypothyroidism – Goitre
(2) Hyperthyroidism-Graves’ disease
(3) Hypersecretion of corticoids – Addison’s disease
(4) Hypersecretion of growth hormone – Gigantism
Answer:
(3) Hypersecretion of corticoids – Addison’s disease
Question 13.
The hormone that stimulates the secretion of HCl and pepsinogen from gastric glands
(1) Gastrin
(2) Insulin
(3) Secretin
(4) Cholecystokinin
Answer:
(1) Gastrin
Question 14.
Which of the following hormones is an amino acid derivative ?
(4) Growth hormone
(1) Insulin
(2) Glucagon
(3) Epinephrine
(4) Growth hormone
Answer:
(3) Epinephrine
Question 15.
Which of the following does not act as a second messenger in hormonal action ?
(1) Cyclic AMP
(2) IP3
(3) FSH
(4) Ca+2
Answer:
(3) FSH
II. Chemical Coordination and Integration Fill in the Blanks (1 Mark)
Question 1.
The non-nutrient chemicals which act as intercellular messengers are called ………..
Answer:
Hormones
Question 2.
Over secretion of …………… hormone leads to gigantism.
Answer:
Growth
Question 3.
The composite gland that acts as both exocrine and endocrine gland is…………
Answer:
Pancreas
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Question 4.
Follicle stimulating hormone and ………… hormone are called gonadotropins.
Answer:
Luteinizing
Question 5.
Iodine is essential for the synthesis of ……….. hormones.
Answer:
Thyroid
Question 6.
The main mineralocorticoid produced by the adrenal cortex in the human body is ………..
Answer:
Aldosterone
Question 7.
Basal metabolic rate is regulated by ………. hormones.
Answer:
Thyroid
Question 8.
The enlargement of ………. gland is called Goitre.
Answer:
Thyroid
Question 9.
Chemically cortisol is a ………. hormone.
Answer:
Steroid
Question 10.
Underproduction of glucocorticoids by adrenal cortex leads to ………. disease.
Answer:
Addison’s
III. Chemical Coordination and Integration One Word Answer Questions (1 Mark)
Question 1.
What are the secretions of the endocrine glands called ?
Answer:
Hormones
Question 2.
Which gland produces melatonin hormone?
Answer:
Pineal gland
Question 3.
Name the bilobed gland located on either side of the trachea.
Answer:
Thyroid
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Question 4.
How many parathyroid glands are found in the human body?
Answer:
Four (4)
Question 5.
Which cells of Islets of Langerhans secrete glucagon hormone ?
Answer:
α (Alpha) cells
Question 6.
Which mineral is essential for the synthesis of thyroid hormones ?
Answer:
Iodine
Question 7.
Which disorder is treated with insulin therapy ?
Answer:
Diabetes mellitus
Question 8.
Which hormone supports pregnancy in women ?
Answer:
Progesterone
IV. Chemical Coordination and Integration Very Short Answer Questions (2 Marks)
Question 1.
Define the following :
A) Endocrine gland
B) Hormone
Answer:
A) Endocrine gland : An endocrine gland is a ductless gland that releases its secretions (hormones) directly into the bloodstream to be transported to target organs.
B) Hormone : A hormone is a non-nutrient chemical messenger produced in trace amounts by endocrine glands that regulate physiological functions of the body.
Question 2.
Which hormonal deficiency is responsible for the following ?
A) Cretinism
B) Diabetes mellitus
Answer:
A) Cretinism : Cretinism is caused due to the deficiency of thyroid hormones, usually resulting from hypothyroidism during pregnancy. This condition often occurs due to a lack of iodine in the mother’s diet. Hypothyroidism during pregnancy causes defective development and maturation of the growing baby leading to stunted growth (cretinism), mental retardation, low intelligence quotient, abnormal skin, deaf-mutism, etc.
B) Diabetes mellitus: Diabetes mellitus is caused by the deficiency or absence of the fromone insulin, which is responsible for regulating blood glucose levels through urine and formation of harmful compounds known as ketone bodies.
Question 3.
What is acromegaly? Name the hormone responsible for this disorder.
Answer:
Acromegaly is a condition caused by excess secretion of growth hormone (GH) in adults leading to abnormal enlargement of bones, especially in the face and limbs.
- Acromegaly may lead to serious complications and premature death if unchecked.
- It is due to hypersecretion of growth hormone (GH) in adults.
Question 4.
Which hormone is called antidiuretic hormone? Write the name of the gland that releases it.
Answer:
The antidiuretic hormone (ADH) is vasopressin. It is released by the posterior pituitary but synthesized in the hypothalamus.
Question 5.
Name the endocrine gland that degenerates in old individuals. What important role does it play in the immune system ?
Answer:
Thymus is the gland that degenerates with age. It secretes thymosins which help in the differentiation of T-lymphocytes and boost immune responses.
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Question 6.
Distinguish between Diabetes mellitus and Diabetes insipidus.
Answer:
| Diabetes Mellitus | Diabetes Insipidus |
| 1. It is due to deficiency of insulin. | 1. It is due to deficiency or failure of ADH (vasopressin). |
| 2. It is characterized by High blood sugar (hyperglycemia), excess glucose and ketone bodies in urine. | 2. It is characterized by excessive urination and dehydration. |
Question 7.
What are “Islets of Langerhans” ?
Answer:
- It is the endocrine part of pancreas. Among the pancreatic acini several/ many cells are present called “Islets of Langerhans”.
- It contains α – cells secrete glucagon and β – cells secrete insulin.
Question 8.
Which gland secretes fight or flight hormones ? Where is it located ?
Answer:
The adrenal medulla secretes adrenaline (epinephrine) and noradrenaline (norepinephrine)-the fight or flight hormones. It is located above each kidney.
Question 9.
What are Androgens ? Which cells of the testes secrete them ?
Answer:
- Androgens are male sex hormones (mainly testosterone) that regulate male secondary sexual characteristics and spermatogenesis.
- They are secreted by the Leydig cells (interstitial cells) of the testes.
E.g. : Testosterone
Question 10.
What is erythropoietin? What is its function?
Answer:
Erythropoietin is a peptide hormone secreted by the juxtaglomerular cells of the kidney. Its function is to stimulate erythropoiesis (formation of red blood cells).
V. Chemical Coordination and Integration Short Answer Questions (4 Marks)
Question 1.
List out the names of the endocrine glands present in human beings and mention the hormones they secrete.
Answer:
The human body has the following endocrine glands :
- Pituitary gland : Secretes growth hormone (GH), prolactin (PRL), Thyroid Stimulating Hormone (TSH), Adrenocorticotropic Hormone (ACTH), Luteinizing Hormone ( LH), Follicle Stimulating Hormone (FSH), Melanocyte Stimulating Hormone (MSH), oxytocin, and vasopressin (ADH).
- Pineal gland: Secretes melatonin which regulates sleep-wake cycles.
- Thyroid gland : Secretes thyroxine (T4), triiodothyronine (T3), and thyrocalci- tonin (TCT).
- Parathyroid glands: Secrete parathyroid hormone (PTH) that regulates blood calcium levels.
- Thymus gland : Secretes thymosins important for T-cell development and immunity.
- Adrenal glands : Medulla secretes adrenaline and noradrenaline; cortex seretes cortisol, aldosterone, and small quantities of androgens.
- Pancreas (Islets of Langerhans): Secretes insulin (p – cells) and glucagon (a – cells).
- Testes: Secrete androgens like testosterone.
- Ovaries: Secrete estrogen and progesterone.
- Other hormone-secreting tissues: Heart (ANF), kidney (erythropoietin), and gastrointestinal tract (gastrin, secretin, CCK, GIP).
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Question 2.
Diagrammatically indicate the location of various endocrine glands in the human body.
Answer:

Question 3.
Write short notes on the functions of the following hormones.
a) Parathyroid hormone b) Aldosterone c) Thymosins d) Insulin
Answer:
a) Parathyroid Hormone (PTH):
- Humans have four parathyroid glands located on the posterior side of the thyroid gland, with one pair in each two lobes of the thyroid.
- These glands secrete a peptide hormone known as parathyroid hormone (PTH), which is regulated by the calcium ion concentration in the blood.
- PTH increases blood calcium (Ca2+) levels by acting on bones to stimulate reasorption or breakdown (demineralization).
- It also promotes reabsorption of Ca2+ in the renal tubules and enhances calcium absorption from the intestines.
- Thus, PTH is called a hypercalcemic hormone as it raises blood calcium levels and works with thyrocalcitonin (TCT) to maintain calcium balance in the body.
b) Aldosterone:
- Aldosterone is the primary mineralocorticoid hormone in the body.
- It acts mainly on renal tubules, promoting the reabsorption of sodium (Na+) and water, while facilitating the excretion of potassium (K+) and phosphate ions.
- Aldosterone plays a key role in maintaining electrolyte balance, fluid volume, osmotic pressure, and blood pressure.
c) Thymosins:
- The thymus is a lobular gland situated between the lungs, behind the sternum, on the ventral side of the aorta.
- It is crucial for the development and maturation of the immune system.
- The thymus secretes a group of peptide hormones known as thymosins.
- Thymosins are essential for the differentiation of T-lymphocytes, providing cell-mediated immunity.
- They also aid in the production of antibodies, supporting humoral immunity.
- In old age, the thymus shrinks, leading to reduced thymosin production and consequently weaker immune responses in elderly individuals.
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d) Insulin:
- Insulin is a peptide hormone that plays a vital role in maintaining blood glucose levels.
- It primarily targets hepatocytes (liver cells) and adipocytes (fat cells), enhancing the uptake and utilization of glucose.
- Insulin also stimulates the conversion of glucose into glycogen (a process called glycogenesis) in the target cells.
- Glucose homeostasis in the blood is regulated by the coordinated action of insulin and glucagon.
Question 4.
Write a note on the mechanism of hormone action.
Answer:
1. Hormone-Receptor Interaction:
i. Hormones exert their effects by binding to specific receptor proteins located in their target tissues.
ii. These receptors can be of two main types :
- Membrane-bound receptors – located on the surface (cell membrane) of target cells.
- Intracellular receptors – located inside the target cells, typically in the nucleus.
iii. When a hormone binds to its receptor, it forms a hormone-receptor complex.
iv. Each receptor is highly specific to a particular hormone.
v. This hormone-receptor complex triggers a cascade of biochemical reactions that ultimately lead to physiological responses in the target tissue.
2. Classification Based on Chemical Nature: Hormones are grouped based on their chemical structure into the following categories :
- Peptides, Polypeptides, and Protein Hormones
Examples : Insulin, Glucagon, Pituitary hormones, Hypothalamic hormones, Thyrocalcitonin (TCT), Parathyroid hormone (PTH), Thymosins. - Steroid Hormones
Examples : Cortisol, Testosterone, Estradiol, Progesterone. - Amino Acid Derivatives (Biogenic Amines)
Examples: Epinephrine. - Iodothyronines (Thyroid Hormones)
- Hormones which interact with membrane-bound receptors normally do not enter the target cell, but generate second messengers (E.g: Cyclic AMP, IP3, Ca++etc.) Which in turn regulate cellular metabolism.
- Hormones which interact with intracellular receptors (E.g: Steroid, Iodothyronines, etc.) mostly regulate gene expression or chromosome function by the interaction of hormone-receptor complex with the genome.
- Cumulative biochemical actions result in physiological and developmental effects.

(a) Diagrammatic representation of mechanism of Protem Hormone

(b) Diagrammatic representation of mechanism of Steroid Hormone
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Question 5.
Describe the role of hypothalamus as a neurosecretory endocrine organ.
Answer:
- It is the Master Endocrine gland of the body.
- The hypothalamus basal part of Diencephalon (part of fore brain) and hypothalamus regulates a wide spectrum of body functions. It contains several groups of neurosecretory cells called nuclei, which produce hormones.
- These hormones regulate synthesis and secretion of anterior pituitary hormones. However, these hormones produced by hypothalamus are of 2 types. Releasing hormones (stimulates secretion of pituitary hormones) and inhibiting hormones (Inhibit secretions of pituitary hormones).
- For example, a hypothalamic hormone called Gonadotrophin releasing hormone (GnRH) stimulates to anterior pituitary for synthesis and release of Gonadotrophins (FSH/LH).
- On the other hand Somatostatin (Growth hormone inhibiting hormone) from hypothalamus inhibits release of growth hormone from anterior pituitary.
- These hormones (Releasing hormone or Inhibiting hormone) originating in hypothalamic neurons, pass through axons of neuron of hypothalamic nuclei and are released from their nerve endings into blood vessels.
- These reach anterior pituitary gland through a portal circulatory system and regulate functions of anterior pituitary.
- Posterior pituitary is under direct neural regulation of hypothalamus.
Question 6.
Give an account of the secretions of the pituitary gland.
Answer:
The pituitary gland is divided into three parts : anterior pituitary (adenohypophysis), intermediate lobe (pars intermedia), and posterior pituitary (neurohypophysis).
1. The anterior pituitary (adenohypophysis) secretes six important hormones :
- Growth Hormone (GH) – promotes overall growth of the body.
- Prolactin (PRL) – stimulates milk production in the mammary glands.
- Thyroid Stimulating Hormone (TSH) – regulates the secretion of thyroid hormones.
- Adrenocorticotropic Hormone (ACTH) – stimulates the adrenal cortex to release cortisol.
- Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH) – regulate the function of the gonads (testes and ovaries).
2. The intermediate lobe (pars intermedia) secretes Melanocyte – Stimulating Hormone (MSH), which controls skin pigmentation.
3. The posterior pituitary (neurohypophysis) stores and releases two hormones Oxytocin and Vasopressin (ADH) – which are synthesized by the hypothalamus.
- Oxytocin causes uterine contractions during childbirth and milk ejection.
- Vasopressin helps in water reabsorption in the kidneys and maintains water balance in the body.
Thus, the pituitary gland plays a vital role in regulating growth, metabolism, reproduction, and fluid balance in the body.
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Question 7.
Explain how hypothyroidism and hyperthyroidism can affect the body.
Answer:
Hypothyroidism:
- It is a condition caused by the deficiency of thyroid hormones T3 & T4 decrease, often due to a lack of iodine in the diet.
- In pregnant women, it can lead to cretinism in the developing baby, resulting in stunted growth, mental retardation, low intelligence quotient (IQ), abnor’mal skin, and deaf-mutism.
- In adult women, hypothyroidism can cause irregular menstrual cycles.
- It may also lead to an enlargement of the thyroid gland, known as “Simple goiter”.
Hyperthyroidism:
- It occurs when there is an excessive secretion of thyroid hormones T3 & T4.
- This can happen due to thyroid cancer or the development of nodules in the thyroid gland.
- A severe form of hyperthyroidism is called ‘Exophthalmic goitre or Graves’ disease, which is characterized by protrusion of the eyeballs, enlargement of the thyroid gland, increased basal metabolic rate (BMR), and weight loss.
- It adversely affects overall body physiology.
Thus, both hypothyroidism and hyperthyroidism significantly disrupt the body’s metabolism, development, and hormonal balance.
Chemical Coordination and Integration Class 11 Extra Questions and Answers
I. Multiple Choice Questions (1 Mark)
Question 1.
Why do steroid hormones act on intracellular receptors while peptide hormones mediate their function through cell surface receptors?
(1) Steroids cannot bind to cell surface proteins
(2) Steroids are not electrostatically stable on membranes
(3) Steroids are hydrophobic, hence can pass the membrane
(4) Steroids are hydrophilic, hence cannot bind proteins
Answer:
(2) Steroids are not electrostatically stable on membranes
II. Fill in the Blanks (1 Mark)
Question 1.
Erythropoiesis is stimulated by a peptide hormone called………..
Answer:
Erythropoietin
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Question 2.
Secretin stimulates secretion of ………. and ……….
Answer:
water, bicarbonate ions
Question 3.
………… (CCK/GIP) inhibits gastric secretion and motility.
Answer:
AGIP
Question 4.
Hormones bind to the specific proteins, i.e., ………… to produce their effects on target tissues.
Answer:
Hormone receptor
Question 5.
Where are the hormone receptors present?
Answer:
Target tissues
Question 6.
………… receptors are present inside the target cell.
Answer:
Intracellular
Question 7.
Give a common biological terms for the following groups on the basis of chemical nature of hormones.
i) Melatonin, Catecholamines, Adrenaline, Nor-adrenaline
ii) ADH, Oxytocin, ACTH, Calcitonin
iii) Insulin, Glucagon, Parathyroid, Relaxin
Answer:
i) Amines
ii) Peptides
iii) Proteins
Question 8.
Name the substance, that integrates and co-ordinates all the metabolic activities within the organism.
Answer:
Hormones
Question 9.
The ………… and the ………… system jointly coordinate and regulate the physiological functions in the body,
Answer:
Neural system, endocrine
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Question 10.
Endocrine glands are also known as ………… glands.
Answer:
Ductless
Question 11.
Name the chemical which is non-nutrient, acts as intercellular messenger and is produced in trace amount.
Answer:
Hormone
Question 12.
The ………… and ………… producing diffused tissues/cells located in different parts of our body constitute the endocrine system.
Answer:
Endocrine glands, hormone
Question 13.
The atrial wall of our heart secretes a peptide hormone called …………
Answer:
Atrial Natriuretic Factor (ANF)
III. One Word Answer Questions (1 Mark )
Question 1.
Name the hormones which are secreted from gastro-intestinal tract.
Answer:
Gastrin, secretin, cholecystokinin (CCK) and Gastric Inhibitory peptide (GIP).
Question 2.
Hormones which interact with membrane bound receptors, generate enzymes.
Answer:
Second messengers.
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Question 3.
Name any four organs other than endocrine system that produce hormones
Answer:
Gastro intestinal tract, liver, kidney and heart.





































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